Immanuel Kant Baltic Federal University

Main research fields of the Laboratory of Immunology and cellular biotechnology

Main research fields of the Laboratory of Immunology and cellular biotechnology

  1. Changes of immune parameters during T-cells vaccination in patients with rheumatoid arthriris / Ivanova I.P., Seledzova G.V., Mamaev S.V., Litvinova L.S., Lopatnikova Yu.A., Sennikov S.V., Seledzov V.I. // Russian Journal of Immunology. – 2011. V. 5 (14). №3-4. P. 341-349.

  2. The impact of age and gender on the indicators of coagulator and vascular thrombocyte hemostasis in patients with II type diabetes mellitus / Kondratieva E.I., Suhanova G.A., Litvinova L.S., Kirienkova E.V., Kretova E.I., Zatolokln P.A. // Klinichescheskaya Laboratornaya Diagnostika – 2011. №8. P. 41-43.

  3. The impact of surgical correction of obesity (laparoscopic gastro-bypass surgery) under metabolic syndrome on the biochemical blood indicators / Kiriyenkova Y.V., Litvinova L.S., Seledzov V.I., Zalotkin P.A., Aksenova N.N. // Klinicheskaia laboratornaia diagnostika. - 2012. V. 12. P. 3-5.

  4. Eosinophil: A modern concept of the kinetics, structure, and function / Kolobovnikova Yu.V., Urazova O.I., Novitsky V.V., Litvinova L.S., Chumakova S.P. // Gematologiya i Transfusiologiya. – 2012. V. 57(1). P. 30-36.

  5. Dose-response effect of steroid hormones on the Gfi1 and U2afil4 gene expression in T lymphocytes at different stages of differentiation / Gutsol A.A.Sokhonevich N.A., Seledtsov V.I., Litvinova L.S. // Molecular Biology. - 2013. V. 47(4). P. 572–580.

  6. Dexamethasone effects on activation and proliferation of immune memory T cells / Gutsol A.A.Sokhonevich N.A., Seledtsov V.I., Litvinova L.S. // Bulletin of Experimental Biology and Medicine. - 2013. V. 155(4). P. 474-476.

  7. The Content of p53 Protein in Tumor Cells by the Action of a Selective Inhibitor of Hsp27 Chaperone in vitro / Kaigorodova E.V., Litvinova L.S., Konovalova E. V., Klimova М.V., Tashireva L.A., Nosareva O. L., Novitskiy V. V. // International Journal of Biology. - 2013. Vol. 5, №3. – P. 13-18.

  8. Features of cytokine-producing ability of peripheral blood mononuclear cells in the metabolic syndrome / Litvinova L.S.Kirienkova E.V., Gazatova N.D., Zatolokin P.A., Vasilenko М.А., Aksenova N.N., Simbirtsev A.S.  // Cytokines and inflammation. – 2013. №3. P. 62-66.

  9. Effects of steroid hormones upon Th1/Th2 cytokine production by CD45RO+ T cells / Gutsol A.A.Litvinova L.S. // Medical Immunology. – 2013. V. 15(3). P. 263-268.

  10. The influence of immunoregulatory cytokines IL-2, IL-7, and IL-15 upon activation, proliferation, and apoptosis of immune memory T-cells in vitro / Litvinova L.S., Sokhonevich N.A., Gutsol A.A., Kofanova K.A. // Cell and Tissue Biology. - 2013. V. 7(6). P. 539-544.

  11. Study of the nanostructure and cytotoxicity of ZrO2 and Al2O3 ceramic implants / Litvinova L., Shupletsova V., Leitsin V., Shusharina N., Botsman S., Kulkov S., Vasyliev R., Zubov D. // Regenerative Medicine. – 2013. V. 8(6s). P. 191–192.

  12. Human endometrial stromal cells: in vitro biological properties under conventional and low oxygen cell culture conditions / Vasyliev R., Zubov D., Rodnichenko A., Litvinova L., Korop Z., Sednev O., Kurmyshov A. // Regenerative Medicine. – 2013. V. 8 (6s). P. 176–177.

  13. Pathogenesis of Insulin Resistance in Metabolic Obesity / Litvinova L.S., Kirienkova E.V., Mazunin I.O., Vasilenko M.A., Fattakhov N.S. // Biochemistry. – 2014. V. 8(3). P. 192-202.

  14. Тhe effects of testosterone and β-estradiol on activation of lymphocytes associated with IL-2 production and expression / Gutsol A.A.Sokhonevich N.A., Kofanova K.A., Litvinova L.S. // Cell and Tissue Biology. – 2014. V. 8(6). P. 473–477.

  15. Evaluating the Number of Mitochondrial DNA Copies in Leukocytes and Adipocytes from Metabolic Syndrome Patients: Pilot Study / Mozhei O.I., Zatolokin P.A., Vasilenko M.A., Litvinova L.S., Kirienkova E.V., Mazunin I.O. // Molecular Biology. – 2014. V. 48(4). P. 589–592.

  16. Role of adiponectin and pro-inflammatory gene expression in adipose tissue chronic inflammation in women with metabolic syndrome [Electronic resource] / Litvinova L.S., Atochin D.N., Vasilenko M.A., Fattakhov N.S., Zatolokin P.A., Kirienkova E.V. // Diabetology & Metabolic Syndrome. – 2014. - Mode of access: http://www.dmsjournal.com/content/6/1/137

  17. Porosity and biocompatibility study of ceramic implants based on ZrO2 and Al2O3 / Litvinova L., Shupletsova V., Leitsin V., Vasyliev R., Zubov D., Buyakov A., Kulkov S. // Conference Collection. International Conference on Physical Mesomechanics of Multilevel Systems 2014. – 2014. V. 1623. P. 347-350.

  18. The role of nitric oxide synthases in the development of mitochondrial dysfunction in metabolic syndrome [Electronic resource]   / Litvinova L.S., Atochin D.N., Fattakhov N.S., Vasilenko M.A., Zatolokin P.A., Kirienkova E.V. // Front Physiol. – 2015. - Mode of access: http://www.frontiersin.org/Physiology/about

  19. Cytokine-Mediated Regulation of Expression of Gfi1 and U2afll4 Genes by Activated T-Cells with Various Differentiation Status In Vitro / Yurova K.A., Sokhonevich N.A., Khaziakhmatova O.G., Litvinova L.S. // Biomedical Chemistry. – 2015. V. 9(2). P. 165-172.

  20. Effects of Immunoregulatory Cytokines (IL-2, IL-7, and IL-15) on Expression of Gfi 1 and U2afl l4 Genes in T Cells at Different Stages of Differentiation / Sokhonevich N.A., Yurova K.A., Gutsol A.A., Khaziakhmatova O.G., Mazunin I.O., Litvinova L.S. // Bulletin of Experimental Biology and Medicine. - 2015. - Vol. 159, No. 2. P. 236 – 239.

  21. Dose-Dependent Effects of Dexamethasone on Functional Activity of T-Lymphocytes with Different Grades of Differentiation / Gutsol A.A., Sokhonevich N.A., Yurova K.A., Khaziakhmatova O.G., Shupletsova V.V., Litvinova L.S. // Molecular Biology. - 2015. Vol. 49, No. 1. P. 130–137.

  22. Phenotypic characterization and functional features of memory T- and B-cells / Sokhonevich N.A., Khaziakhmatova O.G., Yurova K.A., Shupletsova V.V., Litvinova L.S. // Tsitologiia. - 2015. Vol. 57 (5). P. 311-318.

  23. Insulin resistance pathogenesis in metabolic obesity / Litvinova L.S., Kirienkova E.V., Mazunin I.O., Vasilenko M.A., Fattakhov N.S.  // Biomedical Chemistry. – 2015. V. 61(1). P. 70-82.

  24. Nitric oxide and mitochondria in metabolic syndrome / Litvinova L., Atochin D., Fattakhov N., Vasilenko M., Zatolokin P., Kirienkova E. // Frontiers in Physiology, 2015. – Vol. 6. – Mode of access: http://journal.frontiersin.org/article/10.3389/fphys.2015.00020/abstract.


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