IKBFU researchers together with the Regional Clinical Hospital’s doctors have conducted a joint clinical and morphological analysis of papers devoted to the timely diagnosis of pre-tumor processes and early gastric cancer. Malignant neoplasms are one of the most common causes of morbidity and mortality.
Annually there are more than 10 million cases of these diseases registered in the world, and this number keeps growing. Today, public health is facing this global trend.
Since 2017 to 2019 an IKBFU post-graduate and pathologist at Regional Clinical Hospital (RCH) of Kaliningrad Mikhail Shushval under the leadership of the IKBFU laboratory diagnostics head doctor, Doctor of Medical Sciences, Volkova Larisa Vladimirovna have conducted the research. Also doctors of the RCH: candidate of Medical Sciences, Gennadiy Lyashenko and Leonid Nizhnik, together with IKBFU resident Alexey Muratov and IKBFU Medical School students: Anastasia Antishina, Khurshed Abduzhabborov have conducted a research in the field of diagnostics and treatment of precancerous processes and early stomach cancer.
The study is based on the study of materials of endoscopic resection of the gastric mucosa of 62 patients. In most cases, benign epithelial tumors were diagnosed. Nevertheless, among 9 patients oncological changes were revealed - tubular adenomas with mild and severe dysplasia, which is a morphological manifestation of the various stages of gastric carcinogenesis. In 3 patients’ cases, against the background of a hyperplastic polyp and tubular adenomas, highly differentiated adenocarcinoma of the stomach was found. The results of the study were presented in the form of a report (electronic poster) in France in Nice: 31st European Congress of Pathology, Nice, France, and September 7 - 11, 2019.
Mikhail Shushval said:
“Over the past few years, our collaboration with endoscopists has helped to study epithelial tumors of the gastric mucosa in more detail, which contributed to the correct assessment of the macroscopic and microscopic picture of epithelial formations of the stomach. This increases the opportunities for early diagnosis and treatment of tumors and precancerous diseases of the stomach. In our study, we showed that this does not always require the most complex and expensive methods. We believe that for the optimal solution of diagnostic problems an individual approach to each patient is necessary, a correct and adequate assessment of the endoscopic and morphological picture in case of tumors of the stomach. Our work has demonstrated that the traditional method of endoscopic resection of the gastric mucosa, provided that a group of trained medical specialists of various specialties works together, can successfully solve the problems of timely diagnosis and treatment of both precancerous processes and diagnose gastric cancer in the initial stages of its development. Well-coordinated organized work of a group of medical specialists of various profiles is the key to a positive result”.